Fabry disease pain: patient and preclinical parallels
Fabry mice have a loss of nerve fibers in sites including the sciatic nerve, skin, and intestinal mucosa. 81,111,129,146 Nerve fiber loss can occur as early as 10 weeks in mice and declines with age. 129 Similar to humans, mice exhibit less fiber loss in the nerve bundle compared with the skin. 81 Fabry mice have similar motor nerve conduction ...